Thiazides in kidney transplant recipients: skin in the game – Nature Reviews Nephrology

  • Agarwal, R. et al. Chlorthalidone for hypertension in advanced chronic kidney disease. N. Engl. J. Med. 385, 2507–2519 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Georgianos, P. I. & Agarwal, R. Hypertension in chronic kidney disease-treatment standard 2023. Nephrol. Dial. Transplant. 38, 2694–2703 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Moes, A. D., Hesselink, D. A., van den Meiracker, A. H., Zietse, R. & Hoorn, E. J. Chlorthalidone versus amlodipine for hypertension in kidney transplant recipients treated with tacrolimus: a randomized crossover trial. Am. J. Kidney Dis. 69, 796–804 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Taber, D. J. et al. Are thiazide diuretics safe and effective antihypertensive therapy in kidney transplant recipients? Am. J. Nephrol. 38, 285–291 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kramers, B. J. et al. Effects of hydrochlorothiazide and metformin on aquaresis and nephroprotection by a vasopressin v2 receptor antagonist in ADPKD: a randomized crossover trial. Clin. J. Am. Soc. Nephrol. 17, 507–517 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Shao, S. C. et al. Associations of thiazide use with skin cancers: a systematic review and meta-analysis. BMC Med. 20, 228 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • VanWormer, J. J., Abokede, E. B. & Berg, R. L. Hydrochlorothiazide use, sun exposure, and risk of keratinocyte cancer. BMC Public Health 22, 1282 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fuhrmann, J. D. et al. Cancer among kidney transplant recipients >20 years after transplantation: post-transplant lymphoproliferative disorder remains the most common cancer type in the ultra long-term. Clin. Kidney J. 15, 1152–1159 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Letellier, T. et al. Association between use of hydrochlorothiazide and risk of keratinocyte cancers in kidney transplant recipients. Clin. J. Am. Soc. Nephrol. 15, 1804–1813 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bretagnol, A. et al. Autosomal dominant polycystic kidney disease: risk factor for nonmelanoma skin cancer following kidney transplantation. Transpl. Int. 23, 878–886 (2010).

    PubMed 

    Google Scholar
     

  • Nazarzadeh, M. et al. Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis. Lancet 398, 1803–1810 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kucharczyk, P. et al. Thiazides attenuate insulin secretion through inhibition of mitochondrial carbonic anhydrase 5b in β-islet cells in mice. J. Am. Soc. Nephrol. 34, 1179–1190 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Sokooti, S. et al. Association of diuretic use with increased risk for long-term post-transplantation diabetes mellitus in kidney transplant recipients. Nephrol. Dial. Transplant. 37, 1375–1383 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • de Mattos, A. M. et al. Autosomal-dominant polycystic kidney disease as a risk factor for diabetes mellitus following renal transplantation. Kidney Int. 67, 714–720 (2005).

    Article 
    PubMed 

    Google Scholar