In studies, most lung problems occurred in less than 5% of patients taking a single ICI drug. For ICI combinations, this rate is closer to 10%.
The Opdivo+Yervoy clinical trial tracked these side effects in lung cancer patients. About 9% of study patients reported lung inflammation. Standard steroid treatment resolved the condition for most patients. But a few cases were fatal.
Patients should report any suspected lung problems to their doctors as soon as possible. Early detection may help healthcare providers manage the reaction more successfully.
3: Digestive System Complications
Immunotherapy drugs can cause gastrointestinal side effects. These reactions may happen because of inflammation or immune cell attacks in the intestines. Digestive complications are often mild to moderate, but some may become serious.
Digestive system side effects of ICIs include:
- Abdominal pain
- Diarrhea
- Nausea
- Vomiting
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- Source: https://www.mesothelioma.com/blog/worst-side-effects-of-immunotherapy/