Japan

Editor’s Note: We asked authors of Original Investigations to provide short plain-language summaries that would briefly summarize what inspired their...

Cell line generation and growth Human embryonic kidney (HEK) cell lines containing a tetracycline (tet)-inducible expression system (T-REx™; Invitrogen, Carlsbad,...

Animals Wild-type (WT) C57BL/6 mice were purchased from Koatech (Pyeongtaek, South Korea), and P2Y2R KO mice on C57BL/6 background (B6.129P2-P2ry2tm1Bhk/J)...

Kovesdy, C. P. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl () 12, 7–11, doi: (2011). https://doi.org/10.1016/j.kisu.2021.11.003...

Animals Wild-type (WT) C57BL/6 mice were purchased from Koatech (Pyeongtaek, South Korea), and P2Y2R KO mice on C57BL/6 background (B6.129P2-P2ry2tm1Bhk/J)...

Kovesdy, C. P. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl () 12, 7–11, doi: (2011). https://doi.org/10.1016/j.kisu.2021.11.003...

Changes in lifestyle, dietary habits, and occupational patterns have been a major factor in the escalating incidence of metabolic syndrome....

Liyanage, T. et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 385 (9981), 1975–1982 (2015)....

Our study presents the first meta-analysis of only cohort studies examining the risk of CKD in patients with MAFLD. Aggregating...

Animal models Male C57BL/6 mice (21 ± 3 g; 8–12 weeks) were obtained from the Center of Laboratory Animals at...

Animal models Male C57BL/6 mice (21 ± 3 g; 8–12 weeks) were obtained from the Center of Laboratory Animals at...

Caffeine, or 1,3,7-trimethylxanthine is a natural alkaloid commonly found in substances, including tea, coffee, and chocolate; as well as in...