Cancer survival is lower among patients with kidney failure, a recent study finds.
Among the entire cancer population in Australia and New Zealand from 1980-2019, de novo cancer occurred in 4089 patients receiving dialysis and 3253 kidney transplant recipients. Previous research also finds that kidney cancer can lead to kidney failure.
Survival directly or indirectly related to cancer at 5 years was a significant 75% and 45% lower for patients who received dialysis or a kidney transplant, respectively, compared with the general population with cancer, Brenda Maria Rosales, PhD, of The University of Sydney and colleagues reported in Nephrology Dialysis Transplantation. Excess cancer mortality was 2.2- and 1.3-fold higher for patients on dialysis or kidney transplant recipients, respectively.
Cancer-related survival differed by cancer type, the investigators reported. It was significantly lower for patients with vs without kidney failure who had melanoma, breast cancer, or prostate cancer. No excess mortality was observed for lung cancer.
“Decreased cancer survival in kidney failure may reflect differences in multi-morbidity burden, reduced access to treatment, or greater harm from or reduced efficacy of treatments,” Dr Rosales’ team wrote.
References:
Oliveras L, Rosales BM, De La Mata N, et al. Using relative survival to estimate the burden of kidney failure. Nephrol Dial Transplant. 2024 Feb 21:gfae046. doi:10.1093/ndt/gfae046
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