Council E-E, Group EW. Chronic kidney disease is a key risk factor for severe COVID-19: a call to action by the ERA-EDTA. Nephrol Dial Transpl. 2021;36(1):87–94.
Azzi Y, Bartash R, Scalea J, Loarte-Campos P, Akalin E. COVID-19 and solid organ transplantation: a review article. Transplantation. 2021;105(1):37–55.
Kamar N, Abravanel F, Marion O, Couat C, Izopet J, Del Bello A. Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients. N Engl J Med. 2021;385(7):661–2.
Menni C, Valdes AM, Polidori L, Antonelli M, Penamakuri S, Nogal A, Louca P, May A, Figueiredo JC, Hu C, et al. Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study. Lancet. 2022;399(10335):1618–24.
Jayk Bernal A, Gomes da Silva MM, Musungaie DB, Kovalchuk E, Gonzalez A, Delos Reyes V, Martín-Quirós A, Caraco Y, Williams-Diaz A, Brown ML, et al. Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients. N Engl J Med. 2022;386(6):509–20.
Saravolatz LD, Depcinski S, Sharma M. Molnupiravir and nirmatrelvir-ritonavir: oral coronavirus disease 2019 antiviral drugs. Clin Infect Dis. 2023;76(1):165–71.
Grein J, Ohmagari N, Shin D, Diaz G, Asperges E, Castagna A, Feldt T, Green G, Green ML, Lescure FX, et al. Compassionate use of remdesivir for patients with severe Covid-19. N Engl J Med. 2020;382(24):2327–36.
Elec AD, Oltean M, Goldis P, Cismaru C, Lupse M, Muntean A, Elec FI. COVID-19 after kidney transplantation: early outcomes and renal function following antiviral treatment. Int J Infect Dis. 2021;104:426–32.
Elec F, Magnusson J, Elec A, Muntean A, Antal O, Moisoiu T, Cismaru C, Lupse M, Oltean M. COVID-19 and kidney transplantation: the impact of remdesivir on renal function and outcome – a retrospective cohort study. Int J Infect Dis. 2022;118:247–53.
Poznański P, Augustyniak-Bartosik H, Magiera-Żak A, Skalec K, Jakuszko K, Mazanowska O, Janczak D, Krajewska M, Kamińska D. Molnupiravir when used alone seems to be safe and effective as outpatient COVID-19 therapy for hemodialyzed patients and kidney transplant recipients. Viruses. 2022;14(10):2224.
Villamarín M, Márquez-Algaba E, Esperalba J, Perelló M, Los Arcos I, Campany D, Moreso F, Len O. Preliminary clinical experience of molnupiravir to prevent progression of COVID-19 in kidney transplant recipients. Transplantation. 2022;106(11):2200–4.
Sakurai A, Sasaki T, Kato S, Hayashi M, Tsuzuki SI, Ishihara T, Iwata M, Morise Z, Doi Y. Natural history of asymptomatic SARS-CoV-2 infection. N Engl J Med. 2020;383(9):885–6.
Modelli de Andrade LG, de Sandes-Freitas TV, Requião-Moura LR, Viana LA, Cristelli MP, Garcia VD, Alcântara ALC, Esmeraldo RM, Abbud Filho M, Pacheco-Silva A, et al. Development and validation of a simple web-based tool for early prediction of COVID-19-associated death in kidney transplant recipients. Am J Transpl. 2022;22(2):610–25.
Terada M, Ohtsu H, Saito S, Hayakawa K, Tsuzuki S, Asai Y, Matsunaga N, Kutsuna S, Sugiura W, Ohmagari N. Risk factors for severity on admission and the disease progression during hospitalisation in a large cohort of patients with COVID-19 in Japan. BMJ Open. 2021;11(6):e047007.
Wong G, Rowlandson M, Sabanayagam D, Ginn AN, Kable K, Sciberras F, Au E, Draper J, Arnott A, Sintchenko V, et al. COVID-19 infection with the Omicron SARS-CoV-2 variant in a cohort of kidney and kidney pancreas transplant recipients: clinical features, risk factors, and outcomes. Transplantation. 2022;106(9):1860–6.
Radcliffe C, Palacios CF, Azar MM, Cohen E, Malinis M. Real-world experience with available, outpatient COVID-19 therapies in solid organ transplant recipients during the omicron surge. Am J Transpl. 2022;22(10):2458–63.
Raja MA, Mendoza MA, Villavicencio A, Anjan S, Reynolds JM, Kittipibul V, Fernandez A, Guerra G, Camargo JF, Simkins J, et al. COVID-19 in solid organ transplant recipients: a systematic review and meta-analysis of current literature. Transpl Rev (Orlando). 2021;35(1):100588.
Nevejan L, Ombelet S, Laenen L, Keyaerts E, Demuyser T, Seyler L, Soetens O, Van Nedervelde E, Naesens R, Geysels D, et al. Severity of COVID-19 among hospitalized patients: Omicron remains a severe threat for immunocompromised hosts. Viruses. 2022;14(12):2736.
Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, the Northwell C-RC, Barnaby DP, Becker LB, Chelico JD, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020;323(20):2052–9.
Finelli C, Parisi S. The clinical impact of COVID-19 epidemic in the hematologic setting. Adv Biol Regul. 2020;77:100742.
Zheng Y, Li R, Liu S. Immunoregulation with mTOR inhibitors to prevent COVID-19 severity: a novel intervention strategy beyond vaccines and specific antiviral medicines. J Med Virol. 2020;92(9):1495–500.
Appelberg S, Gupta S, Svensson Akusjärvi S, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, et al. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells. Emerg Microbes Infect. 2020;9(1):1748–60.
Khan N, mTOR. A possible therapeutic target against SARS-CoV-2 infection. Arch Stem Cell Ther. 2021;2(1):5–7.
Lopez-Vilella R, Sanchez-Lazaro I, Trenado VD, Edo SL, Dolz LM, Bonet LA. COVID-19 and heart transplantation. Initial experience in a tertiary hospital. Transplant Proc. 2021;53(9):2743-6.
Colmenero J, Rodríguez-Perálvarez M, Salcedo M, Arias-Milla A, Muñoz-Serrano A, Graus J, Nuño J, Gastaca M, Bustamante-Schneider J, Cachero A, et al. Epidemiological pattern, incidence, and outcomes of COVID-19 in liver transplant patients. J Hepatol. 2021;74(1):148–55.
Kijima Y, Shimizu T, Kato S, Kano K, Horiuchi T, Nozaki T, Omoto K, Inui M, Toma H, Iida S et al. Case report of COVID-19 infection after kidney transplant treated with casirivimab-imdevimab and mycophenolate mofetil changed to everolimus. Transplant Proc. 2022;54(6):1561-3.
Kirchner GI, Meier-Wiedenbach I, Manns MP. Clinical pharmacokinetics of everolimus. Clin Pharmacokinet. 2004;43(2):83–95.
Klawitter J, Nashan B, Christians U. Everolimus and sirolimus in transplantation-related but different. Expert Opin Drug Saf. 2015;14(7):1055–70.
Angelico R, Blasi F, Manzia TM, Toti L, Tisone G, Cacciola R. The management of Immunosuppression in kidney transplant recipients with COVID-19 disease: an update and systematic review of the literature. Med (Kaunas). 2021;57(5):435.
Gottlieb RL, Vaca CE, Paredes R, Mera J, Webb BJ, Perez G, Oguchi G, Ryan P, Nielsen BU, Brown M, et al. Early remdesivir to prevent progression to severe Covid-19 in outpatients. N Engl J Med. 2022;386(4):305–15.
Moromizato T, Sakaniwa R, Tokuda Y, Taniguchi K, Shibuya K. Intravenous methylprednisolone pulse therapy and the risk of in-hospital mortality among acute COVID-19 patients: Nationwide clinical cohort study. Crit Care. 2023;27(1):53.
Suzuki Y, Shibata Y, Minemura H, Nikaido T, Tanino Y, Fukuhara A, Kanno R, Saito H, Suzuki S, Inokoshi Y, et al. Real-world clinical outcomes of treatment with molnupiravir for patients with mild-to-moderate coronavirus disease 2019 during the Omicron variant pandemic. Clin Exp Med. 2023;23(6):2715–23.
Hammond J, Leister-Tebbe H, Gardner A, Abreu P, Bao W, Wisemandle W, Baniecki M, Hendrick VM, Damle B, Simón-Campos A, et al. Oral nirmatrelvir for high-risk, nonhospitalized sdults with Covid-19. N Engl J Med. 2022;386(15):1397–408.
Fishbane S, Hirsch JS, Nair V. Special considerations for paxlovid treatment among transplant recipients with SARS-CoV-2 infection. Am J Kidney Dis. 2022;79(4):480–2.
Devresse A, Sébastien B, De Greef J, Lemaitre F, Boland L, Haufroid V, Scohy A, Kabamba B, Yombi JC, Belkhir L, et al. Safety, efficacy, and relapse of nirmatrelvir-ritonavir in kidney transplant recipients infected with SARS-CoV-2. Kidney Int Rep. 2022;7(11):2356–63.
Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, et al. Remdesivir for the treatment of Covid-19 – final report. N Engl J Med. 2020;383(19):1813–26.
Buxeda A, Arias-Cabrales C, Pérez-Sáez MJ, Cacho J, Cabello Pelegrin S, Melilli E, Aladrén MJ, Galeano C, Lorenzo I, Mazuecos A, et al. Use and safety of remdesivir in kidney transplant recipients with COVID-19. Kidney Int Rep. 2021;6(9):2305–15.
Solera JT, Árbol BG, Bahinskaya I, Marks N, Humar A, Kumar D. Short-course early outpatient remdesivir prevents severe disease due to COVID-19 in organ transplant recipients during the omicron BA.2 wave. Am J Transpl. 2023;23(1):78–83.
Leegwater E, Strik A, Wilms EB, Bosma LBE, Burger DM, Ottens TH, van Nieuwkoop C. Drug-induced liver injury in a patient with coronavirus disease 2019: potential interaction of remdesivir with P-glycoprotein inhibitors. Clin Infect Dis. 2021;72(7):1256–8.
Kanazawa N, Terazono H, Shigemi A, Mitsuke A, Nishimura H, Tatarano S, Yamada Y, Enokida H, Takeda Y. Case reports: increase in blood concentration of tacrolimus in patients with renal transplantation under COVID-19 treatment. Jpn J Pharm Health Care Sci. 2022;48(2):106–11.
Mazzola A, Todesco E, Drouin S, Hazan F, Marot S, Thabut D, Varnous S, Soulié C, Barrou B, Marcelin AG, et al. Poor antibody response after two doses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in transplant recipients. Clin Infect Dis. 2022;74(6):1093–6.
Fujieda K, Tanaka A, Kikuchi R, Takai N, Saito S, Yasuda Y, Fujita T, Kato M, Furuhashi K, Maruyama S. Assessment of antibody-titer changes after second and third severe acute respiratory syndrome coronavirus 2 mRNA vaccination in Japanese post-kidney-transplant patients. Vaccines (Basel). 2023;11(1):134.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.
Sato R, Matsuzawa Y, Ogawa H, Kimura K, Tsuboi N, Yokoo T, Okada H, Konishi M, Kirigaya J, Fukui K, et al. Chronic kidney disease and clinical outcomes in patients with COVID-19 in Japan. Clin Exp Nephrol. 2022;26(10):974–81.
Alonso-Navarro R, Ramírez M, Masiá M, Paredes R, Montejano R, Povar-Echeverria M, Carratalà J, Salavert M, Bernal E, Dueñas C, et al. Time from symptoms onset to remdesivir is associated with the risk of ICU admission: a multicentric analyses. BMC Infect Dis. 2023;23(1):286.
Bruno G, Giotta M, Perelli S, De Vita G, Bartolomeo N, Buccoliero GB. Early access to oral antivirals in high-risk outpatients: good weapons to fight COVID-19. Viruses. 2022;14(11):2514.
- The Renal Warrior Project. Join Now
- Source: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-024-03561-7